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The Boye Lab1
AAV: a beautiful and powerful virus2
Dr. Boye and her Genzyme/Sanofi colleagues working together to treat a form of childhood blindness3
Our Research Focus
- to develop AAV-based gene therapy approaches for delivering genes to the outer retina (notably foveal cones) following intravitreal delivery
- to develop an AAV-based gene therapy for treatment of GUCY2D-Leber congenital amaurosis-1 (LCA1)
- to develop dual AAV vector platforms that are capable of delivering large transgenes (> 5kb)
- to develop gene replacement therapies for various forms of Congenital Stationary Night Blindness (CSNB), a disorder caused by mutations in genes which express bipolar cell- specific proteins.
I was so fortunate to be asked to speak at the Fighting Blindness Retina 2015 International Conference, supported by Novartis, which took place in Croke Park, Dublin, Ireland! Sight loss affects ~224,000 […]
Congratulations to Tyler for taking the photo which got the cover of last issue’s Human Gene Therapy. And thank you to the entire Boye lab for contributing to this featured […]
When he’s not busy conducting gene therapy experiments at the bench, our very own K. Tyler McCullough graciously volunteers his time at UF Health where he brightens the day of many a patient […]
Congratulations to Miranda White (soon to be Miranda Scalabrino) on her first, first author publication!
Miranda’s work on developing a gene therapy for Congenital Stationary Night Blindness was just accepted in Human Molecular Genetics. Click here to see the fruits of her labor! http://www.ncbi.nlm.nih.gov/pubmed/26310623
The very first graduate student of the Boye lab will officially become Miranda Scalabrino this December 19th! Congratulations Miranda and Anthony!
“From Bench to Branding: Bringing Research Discoveries to Life”- McKnight Brain Institute, DeWeese Auditorium, 8:00-5:00
In case you’re looking for the Boye lab, we are currently housed in M-119 of the Medical Sciences Building. We brought our capsids with us!
Please stop by the following talks or posters being presented by members of the Boye lab: “AAV-mediated rescue of a mouse model of X-linked Congenital Stationary Night Blindness” Miranda White […]
Please come out to support LCA research by registering for Creed’s Cause 5K at the following link: https://4thannualcreedscause5k.itsyourrace.com/register/default.aspx