Menu UF Health Home Menu
 
Screen Shot 2016-02-11 at 2.55.20 PM

The Boye Lab

Boye lab research was featured in a recent FFB video.

Robert

Visitors like little Robert motivate us to develop cures for blindness

We were so happy to host Janice, Hugh, and Robert in our lab this month. They came all the way from Australia to learn more about our work on GUCY2D-LCA1. […]

Dr. Boye is pleased to be working with a fantastic team at Genzyme/Sanofi to develop a treatment for a form of childhood blindness
Prev Next

Our Research Focus

HGT art
The focus of our research is developing viral vector-based gene replacement strategies for the treatment of inherited ocular disease. Our current goals are:

  • to develop AAV-based gene therapy approaches for delivering genes to the outer retina (notably foveal cones) following intravitreal delivery
  • to develop an AAV-based gene therapy for treatment of GUCY2D-Leber congenital amaurosis-1 (LCA1)
  • to develop dual AAV vector platforms that are capable of delivering large transgenes (> 5kb)
  • to develop gene replacement therapies for various forms of Congenital Stationary Night Blindness (CSNB), a disorder caused by mutations in genes which express bipolar cell- specific proteins.

Recent News

PARVO 2016

The Boye lab was represented by both Sanford Boye and Tyler McCullough at this year’s PARVO meeting in Corsica. Sanford presented our work,  “Modifying the AAV capsid for increased transduction following intravitreal injection” […]

Dr. Boye is awarded the 2016 MOMS for Sight Visionary Award

At their annual ‘Black Ties and Blindfolds’ fundraiser, Dr. Boye was honored with this award for her dedication to education, research, and support of the visually impaired community. Thank you […]

Congratulations Dr. Choudhury for being awarded ‘Best in Group’ at the 4th annual Postdoc Research Symposium!

Shreyasi won this award for her poster presentation entitled “Novel Methodology for Creating Primate Retina with Sortable Cell Populations”.  Well done representing the lab, the Department and the College!

Congratulations to our SUPERIOR grants administrator, Doug Perkinson

Thank you for all that you do to support the Boye lab. You are an invaluable (and superior!) part of the team! 

Boye Lab publishes new study in JVI investigating the role of HSPG in retinal transduction by intravitreally delivered AAVs

To view this article, please click here: http://www.ncbi.nlm.nih.gov/pubmed/26865709

Upcoming Events

Dr. Scalabrino’s Commencement Ceremony

We are excited to celebrate our newest doctor at the Annual College of Medicine Graduate Convocation on Thursday, April 28, 11:00-12:00. Miranda and I will be tirelessly practicing the hooding […]

ARVO- Seattle

Looking forward to presenting Boye Lab research May 1st-5th in Seattle! Sunday, May 1st, 1:30-3:15: Shreyasi Choudhury’s poster, “Novel Methodology for Creating Primate Retina with Sortable Cell Populations: Monday, May 2nd, […]

Miranda Scalabrino’s Final Defense- March 18th, 9:00 am

Please join me on Friday, March 10th at 9:00 am in C1-4 of the Communicore for Miranda’s seminar entitled, “Adeno Associated Viral Gene Therapy Targeting On Bipolar Cells Restores Function in […]

MIRANDA’S WEDDING!

The very first graduate student of the Boye lab will officially become Miranda Scalabrino this December 19th! Congratulations Miranda and Anthony!

Center for Vision Research Annual Symposium 11-2-15

“From Bench to Branding: Bringing Research Discoveries to Life”- McKnight Brain Institute, DeWeese Auditorium, 8:00-5:00