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Dr. Boye is pleased to be working with a fantastic team at Genzyme/Sanofi to develop a treatment for a form of childhood blindness
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Our Research Focus

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The focus of our research is developing viral vector-based gene replacement strategies for the treatment of inherited ocular disease. Our current goals are:

  • to develop AAV-based gene therapy approaches for delivering genes to the outer retina (notably foveal cones) following intravitreal delivery
  • to develop an AAV-based gene therapy for treatment of GUCY2D-Leber congenital amaurosis-1 (LCA1)
  • to develop dual AAV vector platforms that are capable of delivering large transgenes (> 5kb)
  • to develop gene replacement therapies for various forms of Congenital Stationary Night Blindness (CSNB), a disorder caused by mutations in genes which express bipolar cell- specific proteins.

Recent News

Congratulations to Doctoral Candidate Miranda White

On October 23rd, Miranda White passed her qualifying exam and officially became a ‘doctoral candidate’. Congratulations!

Dr. Boye featured in Genzyme/Sanofi Press Release

The collaborative efforts between Dr. Boye and Genzyme to develop a gene therapy for GUCY2D LCA1 were recently featured in a press release. A link to the aritcle can be found […]

The Boye lab grows by two!

The team is happy to welcome its two newest members. In August, postdoctoral associate Shreyasi Choudhury, Ph.D. and laboratory assistant Tyler McCullough, M.S. joined the group. They bring with them valuable experience […]

Upcoming Events

Center for Vision Research Seminar 11/19/14

“High Resolution Transcriptomics: Dissecting the Molecular Program Underlying Retinal Development”- Rahul Kanadia

ARVO abstract Deadline

DECEMBER 5th!!! Here we come Denver!

17th Annual Vision Research Symposium

Presented by the Center for Vision Research and Institute on Aging “Mitochondrial Function and Metabolism in Aging and Vision” McKnight Brain Institute DeWeese Auditorium (LG-101A) December 8, 2014, 8:00-5:00