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Dr. Boye is pleased to be working with a fantastic team at Genzyme/Sanofi to develop a treatment for a form of childhood blindness
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Our Research Focus

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The focus of our research is developing viral vector-based gene replacement strategies for the treatment of inherited ocular disease. Our current goals are:

  • to develop AAV-based gene therapy approaches for delivering genes to the outer retina (notably foveal cones) following intravitreal delivery
  • to develop an AAV-based gene therapy for treatment of GUCY2D-Leber congenital amaurosis-1 (LCA1)
  • to develop dual AAV vector platforms that are capable of delivering large transgenes (> 5kb)
  • to develop gene replacement therapies for various forms of Congenital Stationary Night Blindness (CSNB), a disorder caused by mutations in genes which express bipolar cell- specific proteins.

Recent News

Congratulations to Miranda White for receiving a travel award to the 2015 ASGCT meeting

Miranda White received a competitive oral presentation slot and a travel award to attend this year’s American Society of Gene and Cell Therapy (ASGCT) meeting. Nice job! Her talk, “Optimization […]

Dr. Boye’s research on LCA1 featured in Ivanhoe News

A link to the article “Gene Therapy: Hope for the Blind?” can be found here:

Congratulations to Doctoral Candidate Miranda White

On October 23rd, Miranda White passed her qualifying exam and officially became a ‘doctoral candidate’. Congratulations!

Dr. Boye featured in Genzyme/Sanofi Press Release

The collaborative efforts between Dr. Boye and Genzyme to develop a gene therapy for GUCY2D LCA1 were recently featured in a press release. A link to the aritcle can be found […]

The Boye lab grows by two!

The team is happy to welcome its two newest members. In August, postdoctoral associate Shreyasi Choudhury, Ph.D. and laboratory assistant Tyler McCullough, M.S. joined the group. They bring with them valuable experience […]

Upcoming Events

Boye lab research being presented at ARVO 2015

Please stop by the following talks or posters being presented by members of the Boye lab: “AAV-mediated rescue of a mouse model of X-linked Congenital Stationary Night Blindness” Miranda White […]

Creed’s Cause 5K- May 2nd, 2015

Please come out to support LCA research by registering for Creed’s Cause 5K at the following link:

Celebration of Research

On February 9th, 2015, the Boye lab will be presenting 3 major research projects at the UF College of Medicine’s Celebration of Research. Join us in the O’Connell center to […]

Center for Vision Research Seminar 11/19/14

“High Resolution Transcriptomics: Dissecting the Molecular Program Underlying Retinal Development”- Rahul Kanadia

ARVO abstract Deadline

DECEMBER 5th!!! Here we come Denver!