Genome-editing technologies that correct specific mutations represent a transformative new approach for treating genetic disorders. Despite its widespread use in mouse models of disease, and in cell lines, the Boye lab was the first to demonstrate the effects of CRISPR/Cas9 mediated gene editing in somatic cells of non-human primate. Their…
“When you get where you’re goin’, don’t forget turn back around. Help the next one in line. Always stay humble and kind”. These lyrics from Tim McGraw (yes, I like him, so what?!) remind me of Mavis Agbandje-McKenna. She is the queen of AAV… she’s basically the queen of…
Doctoral candidate Kaitlyn Calabro had the pleasure of presenting her work this week at the Retinal Degeneration meeting in Ireland. She summarized her efforts to characterize a novel mouse model of Usher syndrome 1B and the effects of dual AAV-MYO7A vectors in these mice and in macaque. She fits…
Kaitlyn Calabro was recently awarded a Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship. The overall goal of Kaitlyn’s proposal, “Exploring MYO7A function in novel mouse models and improving AAV-Dual Vector Gene Therapy for Usher Syndrome 1B” is to generate the necessary preclinical data to initiate…
Shannon E. Boye, PhD ’06, has an eye for tackling some of the toughest sight-robbing vision problems.
The Boye Lab congratulates its newest doctoral candidate, Tyler McCullough! He passed his qualifying exam with flying colors and is slated to fast track to graduation! Congrats Tyler! Additional congrats are in order for his first paper presentation at an international conference (ARVO, Honolulu 2018)!…
Proving that we can effectively bridge our clinical and research faculty, Valentina was awarded 1st place for Outstanding Achievement in the Resident Research Symposium at the Master’s in Ophthalmology Meeting this past weekend in Orlando. She was recognized by the Florida Society of Ophthalmology for her efforts in evaluating…
Shannon Boye, PhD, University of Florida, talks about the advancement of her of gene therapy for Leber congenital amaurosis toward a clinical trial.
Tyler presented his work to develop an AAV-CRISPR/Cas9- based therapy for autosomal dominant CORD6 at this week’s College of Medicine Biomedical Sciences seminar series. Despite looking somewhat sad to be discussing phototransduction here, he was actually quite excited! …
This award is presented to investigators 45 yrs old or younger who are working in areas of translational research. It honors Dr. Carl Camras, who is highly respected for his work as a glaucoma specialist and a research scientist. This award, which was established in 2010, is supported by…
