Miranda L. Scalabrino, Ph.D.

Current Position
Miranda White

Postdoctoral Research Assistant
University of North Carolina, Chapel Hill
Laboratory of Aravind Asokan, Ph.D.

About

Miranda White graduated from Auburn University with a B.S. in Microbial, Molecular, and Cell Biology. During her time in the Boye lab, she focused  on targeting gene therapy vectors specifically to bipolar cells in several models of inherited retinal disease.

Publications (during grad school):

  • Shreyasi Choudhury, Christianne E. Strang, John J. Alexander, Miranda L. Scalabrino, Julie Lynch Hill, Daniel T. Kasuga, C. Douglas Witherspoon, Sanford L. Boye, Paul D. Gamlin, and Shannon E. Boye. Novel Methodology for Creating Macaque Retinas with Sortable Cell Populations. Frontiers Neuroscience, in press
  • Scalabrino ML, Boye SL, Fransen KM, Noel JM, Dyka FM, Min SH, Ruan Q, de Leeuw CN, Simpson EM, Gregg RG, McCall MA, Peachey NS, Boye SE. Intravitreal delivery of a novel AAV vector targets ON bipolar cells and restores visual function in a mouse model of complete Congenital Stationary Night Blindness. Hum Mol Genet. 2015 Aug 26. pii: ddv341. [Epub ahead of print]
  • Sanford Boye, Antonette Bennett, Miranda Scalabrino, James Peterson, Seok Hong Min, Jingfen Sun, Mavis Agbandje-McKenna, Shannon E. Boye. The role of heparan sulphate in transduction of intravitreally delivered AAV vectors. submitted July 2015

Oral Presentations (during grad school):

  • ML White, SL Boye, FM Dyka, S Min, Q Ruan, KM Fransen, CN de Leeuw, EM Simpson, MA. McCall, NS Peachey, SE Boye. “Optimization of rAAV to target ON bipolar cells and to rescue the nobnyx mouse, an animal model of X-linked Congenital Stationary Night Blindness.” American Society of Gene and Cell Therapy Annual Conference, New Orleans, LA, May 2015.
  • ML White, SL Boye, FM Dyka, S Min, Q Ruan, KM Fransen, CN de Leeuw, EM Simpson, MA. McCall, NS Peachey, SE Boye.AAV-mediated rescue of a mouse model of X-linked Congenital Stationary Night Blindness. Association of Research in Vision and Ophthalmology Annual Conference, Denver, CO, May 2015
  • ML While. University of Florida Interdisciplinary Program in Biomedical Sciences Seminar, Gainesville, FL. AAV-mediated rescue of a mouse model of X-linked Congenital Stationary Night Blindness. January 2015.
  • White ML , Dyka FM, de Leeuw CN, Min S, Ruan Q, Boye SL, Hauswirth WW, Peachey NS, Simpson EM, and Boye SE. Optimizing rAAV vectors to target ON bipolar cells. [Invited Data Blitz Presentation & Poster] FASEB Neurobiology and Visual Processing, Saxtons River, VT, June 2014.

Poster Presentations (during grad school):

  • Choudhury S, Manek R, White M, Sun J, Aslanidi G, Svrivistava A, Boye SL, Boye SE. Rational Design of AAV Vectors For Efficient Transduction of Müller Cells. Association of Research in Vision and Ophthalmology Annual Conference, Denver, CO, May 2015.
  •  White ML, Dyka FM, de Leeuw CN, Min S, Ruan Q, Boye SL, Hauswirth WW, Peachey NS, Simpson EM, and Boye SE. Optimizing rAAV vectors to target ON bipolar cells. Association of Research in Vision and Ophthalmology Annual Conference, Orlando, FL, May 2014.
  • Boye SL, White M, Bennett A ,VanVliet K, Dinculescu A, Min S, Peterson J, Agbandje-McKenna M, and Boye SE. Heparan sulfate affinity dictates transduction of photoreceptors from the vitreous by capsid mutated AAV2 variant. Association of Research in Vision and Ophthalmology Annual Conference, Orlando, FL, May 2014.
  • White ML, Dyka FM, de Leeuw CN, Min S, Ruan Q, Boye SL, Hauswirth WW, Peachey NS, Simpson EM, and Boye SE. Optimizing rAAV vectors to target ON bipolar cells.University of Florida College of Medicine Celebration of Research, Gainesville, FL, March 2014.
  • E Ogburn, TW Hill, L Jackson-Hayes, DM Loprete, M White, B Chavez, C Groover and M Pluta. Signalling through the Aspergillus nidulans orthalogue of PKC mediates septum formation. American Society of Biochemistry and Molecular Biology Annual Conference, Anaheim, CA, April 2010
  • Groover C, White M, Loprete DM, Hill TW, Jackson-Hayes LM. Promoter replacement of genes regulating cytokinesis in the filamentous fungus Aspergillus nidulans. Rhodes College Undergraduate Research and Creative Activity Symposium, Memphis, TN, April 2010.
  • White, M, Shang K, Hill TW. Rhodes College Undergraduate Research and Creative Activity Symposium, Memphis, TN, April 2009.

Awards and Recognition (during grad school):

  • 2015- Travel Award, American Society of Gene & Cell Therapy Annual Meeting
  • 2015- Travel Award, University of Florida Graduate Student Council
  • 2014-present- National Eye Institute Vision Sciences T32 Training Grant, University of Florida
  • 2014- Travel Award, FASEB Retinal Neurobiology and Visual Processing
  • 2011-2012- Alabama Association of Food Protection Scholarship
  • Fall 2010, Spring 2012- Auburn University College of Math and Sciences Dean’s List
  • 2010-2011- Auburn University College of Math and Sciences Student Scholarship

Teaching (during grad school):

  • 2015- Student Science Training Program at University of Florida Instructor- Gene Therapy
  • 2014- Student Science Training Program at University of Florida Instructor- Gene Therapy
  • 2012- Auburn University Department of Animal Sciences Teaching Assistant- Food Microbiology Lab
  • 2011-2012- Auburn University Department of Biological Sciences Lab Assistant- Freshman Biology Courses
  • Mentoring experience: I have aided in the mentoring of 5 undergraduate research volunteers and 2 Ph.D. rotation students from 2013-present

Service (during grad school):

  • 2015- present- Student Advisor, University of Florida Interdisciplinary Program in Biomedical Sciences
  • Fall 2014- Co-organizer, Orlando/Jacksonville Chapter Foundation for Fighting Blindness Meeting
  • 2013-2015- Secretary, University of Florida College of Medicine Graduate Student Organization